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GSR Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14115

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms GLR1,GLUR,Glutathione reductase,Glutathione reductase mitochondrial,Glutathione reductase,mitochondrial,GR,Gr1,GRase,GRD 1,GRD1,GSHR,GSR,MGC78522,GSR抗体
    Swissprot P00390
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human GSR
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:1000-1:5000;IHC,,1:50-1:200;
    Concentration 0.4 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm and Mitochondrion.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
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