GSTM2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40444
宿主: Rabbit
反应性: R
应用: WB
Overview
| Synonyms | Glutathione S alkyltransferase M2, Glutathione S transferase 4, Glutathione S transferase M1, GST class mu 2, GST muscle, GST4, GSTM, GSTM2, GTHMUS,GSTM2抗体 |
| Swissprot | P08010 |
| Source | Rabbit |
| Reactivity | Rat |
| Immunogen | Recombinant Rat Glutathione S-transferase Mu 2 protein |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB 1:500-1:1000 |
| Concentration | 0.14mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. |
