HCK Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14119
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | Bmk,Hck 1,Hck,HCK,Hemopoietic cell kinase,JTK9,p59-HCK/p60-HCK,p59Hck,p59HCK/p60HCK,p61Hck,Tyrosine protein kinase HCK,Tyrosine-protein kinase HCK,HCK抗体 |
| Swissprot | P08631 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human HCK |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:200-1:1000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. Cytoplasm. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated and Membrane. Membrane>caveola. 20% of this isoform is associated with caveolae, this association depends on palmitoylation of cyteine at position 3. |
| Tissue specificity | Expressed predominantly in cells of the myeloid and B-lymphoid lineages. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the Src family of tyrosine kinases.This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages.It may help couple the Fc receptor to the activation of the respiratory burst.In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils.Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. |
