HDAC1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18230
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | DKFZp686H12203,GON 10,HD1,HDAC 1,HDAC1,HDAC1,Histone deacetylase 1,Reduced potassium dependency yeast homolog like 1,RPD3,RPD3L1,HDAC1抗体 |
Swissprot | Q13547 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human HDAC1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
Concentration | 1.02mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |