HDAC1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70201
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | DKFZp686H12203,GON 10,HD1,HDAC 1,HDAC1,HDAC1,Histone deacetylase 1,Reduced potassium dependency yeast homolog like 1,RPD3,RPD3L1,HDAC1抗体 |
| Swissprot | Q13547,O09106,Q4QQW4 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse HDAC1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:1000 |
| Concentration | 310 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Ubiquitous, with higher levels in heart, pancreas and testis, and lower levels in kidney and brain.Highest expression level in colonic mucosa. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
Images
Immunohistochemistry analysis of paraffin-embedded human lung cancer using HDAC1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human breast cancer using HDAC1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse testis using HDAC1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat brain using HDAC1 Polyclonal Antibody at dilution of 1:300.
