HDAC6 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-14126
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | CPBHM,FLJ16239,HD 6,HD6,HDAC 6,HDAC6,HDAC6,Histone deacetylase 6 (HD6),Histone deacetylase 6,JM 21,JM21,KIAA0901,OTTHUMP00000032398,OTTHUMP00000197663,PPP1R90,Protein phosphatase 1 regulatory subunit 90,HDAC6抗体 |
Swissprot | Q9UBN7 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant protein of human HDAC6 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.8 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. Cytoplasm. It is mainly cytoplasmic, where it is associated with microtubules. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. |