Histone H1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-31676
宿主: Rabbit
反应性: H,M
应用: WB,IHC-p,IF
Overview
| Synonyms | HIST1H1B,H1F5,Histone H1.5,Histone H1a,Histone H1b,Histone H1s-3,HIST1H1D,H1F3,Histone H1.3,Histone H1c,Histone H1s-2,HIST1H1E,H1F4,Histone H1.4,Histone H1b,Histone H1s-4,Histone H1抗体 |
| Swissprot | P16401,P16402,P10412 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from human Histone H1 around the non-phosphorylation site of Thr17. |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:200-1:1000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Extracellular region or secreted,extracellular exosome,Nucleus,nuclear heterochromatin,nuclear nucleosome,nucleus |
| Tissue specificity | Ubiquitous. Expressed in the majority of the cell lines tested and in testis.1 Publication |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling. |
