HK2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14706
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | DKFZp686M1669,Hexokinase 2,Hexokinase 2 muscle,Hexokinase type II,Hexokinase-2,HK 2,HK II,HK2,HKII,HxK 2,HxK2,HXK2,Muscle form hexokinase,HK2抗体 |
| Swissprot | P52789 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human HK2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:100-1:300; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding. |
| Tissue specificity | Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. |
Images
Western Blot analysis of A431, K562, 231, hela and hepG2 cell using HK2 Polyclonal Antibody at dilution of 1:1200
Immunohistochemistry of paraffin-embedded Human thyroid cancer using HK2 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer using HK2 Polyclonal Antibody at dilution of 1:60
客户发表文献
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样品类型: DL cell
