HLA-DPA1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18082
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | DP(W3),DP(W4),HLA class II histocompatibility antigen DP alpha 1 chain,HLA class II histocompatibility antigen DP alpha chain ,HLA DP1A,HLA DPA 1,HLA SB alpha chain,HLADP,HLADPA1 ,HLASB,HLASB histocompatibility type,Human MHC class II HLA SB alpha gene,Major histocompatibility complex class II DP alpha 1,MHC class II antigen,MHC class II DP3 alpha,MHC class II DPA1,MHC class II HLA DPA1 antigen,PLT1,Primed lymphocyte test 1,HLA-DPA1抗体 |
| Swissprot | P20036 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human HLA-DPA1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
| Concentration | 0.96mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Type I membrane protein; Cell Membrane, Endoplasmic reticulum and Golgi Apparatus |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
