HNF4A Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18087
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | FLJ39654,FRTS4,Hepatic nuclear factor 4 alpha,Hepatocyte nuclear factor 4 alpha,Hepatocyte nuclear factor 4,Hepatocyte nuclear factor 4-alpha,HNF 4 alpha,HNF 4,HNF-4-alpha,HNF4,HNF4A,HNF4A,HNF4a7,HNF4a8,HNF4a9,Hnf4alpha,HNF4alpha10/11/12,MODY 1,MODY,MODY1,NR2A1,NR2A21,Nuclear receptor subfamily 2 group A member 1,OTTHUMP00000031060,OTTHUMP00000031062,TCF 14,TCF,TCF-14,TCF14,Tcf4,Transcription factor 14,hepatic nuclear factor,Transcription factor 14,Transcription factor HNF 4,Transcription factor HNF-4,Transcription factor HNF4,HNF4A抗体 |
Swissprot | P41235 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human HNF4A |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:40-1:200 |
Concentration | 1.2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. |