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HNF4A Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18087

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • 文献(1)
  • Overview

    Synonyms FLJ39654,FRTS4,Hepatic nuclear factor 4 alpha,Hepatocyte nuclear factor 4 alpha,Hepatocyte nuclear factor 4,Hepatocyte nuclear factor 4-alpha,HNF 4 alpha,HNF 4,HNF-4-alpha,HNF4,HNF4A,HNF4A,HNF4a7,HNF4a8,HNF4a9,Hnf4alpha,HNF4alpha10/11/12,MODY 1,MODY,MODY1,NR2A1,NR2A21,Nuclear receptor subfamily 2 group A member 1,OTTHUMP00000031060,OTTHUMP00000031062,TCF 14,TCF,TCF-14,TCF14,Tcf4,Transcription factor 14,hepatic nuclear factor,Transcription factor 14,Transcription factor HNF 4,Transcription factor HNF-4,Transcription factor HNF4,HNF4A抗体
    Swissprot P41235
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human HNF4A
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:40-1:200
    Concentration 1.2mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
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