ICA1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53153
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | 69 kDa islet cell autoantigen,Diabetes mellitus type I autoantigen,ICA 1,Ica1,ICA69,ICA69,ICAp69,Islet cell autoantigen 1 (69kD),Islet cell autoantigen 1 69kDa,Islet cell autoantigen 1,Islet cell autoantigen 1 isoform,Islet cell autoantigen p69,OTTHUMP00000200933,OTTHUMP00000200934,OTTHUMP00000200941,OTTHUMP00000200993,p69,ICA1抗体 |
| Swissprot | Q05084 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human ICA1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:100 |
| Concentration | 0.84mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>cytosol. Golgi apparatus membrane. Cytoplasmic vesicle>secretory vesicle membrane. Cytoplasmic vesicle>secretory vesicle>synaptic vesicle membrane. Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. |
