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IFNB1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19507

宿主: Rabbit

反应性: H

应用: IHC

  • 详情
  • Overview

    Synonyms beta-interferon,Fibroblast interferon,IFB,IFF,IFN beta,IFN-beta,IFNB 1,IFNB,IFNB,IFNB1,Interferon beta 1 fibroblast,Interferon beta,Interferon beta precursor,MGC96956,IFNB1抗体
    Swissprot P01574
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human IFNB1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
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