IFNB1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19507
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | beta-interferon,Fibroblast interferon,IFB,IFF,IFN beta,IFN-beta,IFNB 1,IFNB,IFNB,IFNB1,Interferon beta 1 fibroblast,Interferon beta,Interferon beta precursor,MGC96956,IFNB1抗体 |
Swissprot | P01574 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human IFNB1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. |