IGF1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70301
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | IBP1,IGF I,IGF IA,IGF IB,IGF-I,Igf1,IGF1,IGF1A,IGFI,IGFIA,Insulin like growth factor 1 (somatomedin C),Insulin like growth factor 1,Insulin like growth factor IA,Insulin like growth factor IB,Insulin-like growth factor I,Mechano growth factor,MGF,OTTHUMP00000195080,OTTHUMP00000195081,OTTHUMP00000195082,OTTHUMP00000195083,OTTHUMP00000195084,Somatomedia C,Somatomedin C,Somatomedin-C,IGF1抗体 |
| Swissprot | P05017 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse IGF1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:300-1:1000 |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Tissue specificity | Highest expression level in stria vascularis of cochlear duct |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | IGF1, also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF-1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF-1A. |
Images
Immunohistochemistry analysis of paraffin-embedded human liver cancer using IGF1 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded human kidney cancer using IGF1 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded human lymph nodes cancer using IGF1 Polyclonal Antibody at dilution of 1:500.
