IL18BP Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13876
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | I18BP,IL-18BP,IL18 BP,IL18 BPa,IL18BP,IL18BPa,Interleukin 18 binding protein,Interleukin-18-binding protein,MC51L 53L 54L homolog gene product,Tadekinig alfa,Tadekinig-alfa,IL18BP抗体 |
| Swissprot | O95998 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human IL18BP |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Tissue specificity | Strongly expressed in heart, lung, placenta and spleen. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
