IL1A Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-14153
宿主: Rabbit
反应性: H
应用: WB,IHC,ELISA
Overview
Synonyms | BAF,FAF,Hematopoietin 1,Hematopoietin-1,IL 1 alpha,IL 1A,IL-1 alpha,Il-1a,IL1 ALPHA,IL1,IL1A,IL1A,IL1F1,Interleukin 1 alpha,Interleukin-1 alpha,Interleukin1 alpha,LAF,LEM,Preinterleukin 1 alpha,Pro interleukin 1 alpha,IL1A抗体 |
Swissprot | P01583 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant protein of human IL1A |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease |
Images
Western Blot analysis of Jurkat cell using IL1A Polyclonal Antibody at dilution of 1:666
Immunohistochemistry of paraffin-embedded Human colon cancer using IL1A Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human thyroid cancer using IL1A Polyclonal Antibody at dilution of 1:60