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IL36A Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18108

宿主: Rabbit

反应性: H,M

应用: WB,IHC

  • 详情
  • Overview

    Synonyms FIL1,FIL1 epsilon,FIL1(EPSILON),FIL1E,IL 1 epsilon,IL 1F6,IL 1H1,IL-1 epsilon,IL-1F6,IL1E,IL1F6,IL1F6,IL1RP2,IL36A,Interleukin 1 epsilon,Interleukin 1 family member 6 (epsilon),Interleukin 1 family member 6,Interleukin 36 alpha,Interleukin-1 epsilon,Interleukin-1 family member 6,MGC129552,MGC129553,MGC151479,MGC151481,OTTMUSP00000012798,RP23-176J12.4,IL36A抗体
    Swissprot Q9UHA7
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human IL36A
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:30-1:150;
    Concentration 0.78mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background IL36A (Interleukin 36, Alpha) is a Protein Coding gene. Diseases associated with IL36A include Psoriasis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
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