Insulin Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70202
宿主: Rabbit
反应性: M
应用: IHC
Overview
| Synonyms | IDDM,IDDM1,IDDM2,ILPR,ins,INS,Insulin A chain,Insulin B chain,IRDN,MODY10,Preproinsulin,Proinsulin,Proinsulin precursor,Insulin抗体 |
| Swissprot | P01325 |
| Source | Rabbit |
| Reactivity | Mouse |
| Immunogen | Recombinant protein corresponding to Mouse insulin |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:1000 |
| Concentration | 300 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Tissue specificity | Highest expression level in islet of Langerhans |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Insulin is a peptide hormone,produced by beta cells of the pancreas,and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization,protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule,proinsulin,which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin,while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form. |
