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IRAK3 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14167

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms ASRT5,IL 1 receptor associated kinase M,IL-1 receptor-associated kinase M,IL1 receptor associated kinase M,Interleukin 1 receptor associated kinase 3,Interleukin 1 receptor associated kinase M,Interleukin-1 receptor-associated kinase 3,IRAK M,IRAK-3,IRAK-M,Irak3,IRAK3,IRAK3抗体
    Swissprot Q9Y616
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Recombinant protein of human IRAK3
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 0.6 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus,Other locations:cytoplasm
    Tissue specificity Expressed predominantly in peripheral blood lymphocytes.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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