IRAK3 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-14167
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | ASRT5,IL 1 receptor associated kinase M,IL-1 receptor-associated kinase M,IL1 receptor associated kinase M,Interleukin 1 receptor associated kinase 3,Interleukin 1 receptor associated kinase M,Interleukin-1 receptor-associated kinase 3,IRAK M,IRAK-3,IRAK-M,Irak3,IRAK3,IRAK3抗体 |
Swissprot | Q9Y616 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Recombinant protein of human IRAK3 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.6 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus,Other locations:cytoplasm |
Tissue specificity | Expressed predominantly in peripheral blood lymphocytes. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. |