IRF5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19512
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | Interferon regulatory factor 5,Interferon regulatory factor 5 bone marrow variant,IRF 5,IRF-5,Irf5,IRF5,SLEB10,IRF5抗体 |
| Swissprot | Q13568 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human IRF5 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 0.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | IRF5,also named as SLEB10,contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. I t is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10). |
Images
Western blot analysis of NIH/3T3 Hela Jurkat Hepg2 and A549 cell lysates using IRF5 Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using IRF5 Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using IRF5 Polyclonal Antibody at dilution of 1:25(×200)
