IRS2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17345
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | Insulin receptor substrate 2,IRS 2,IRS-2,Irs2,IRS2,IRS2抗体 |
Swissprot | Q9Y4H2 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Synthetic peptide of human IRS2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-200 |
Concentration | 0.6mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm>cytosol. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. |