ISCU Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18785
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | 2310020H20Rik,HML,hnifU,Iron sulfur cluster assembly enzyme ISCU mitochondrial,Iron sulfur cluster scaffold homolog (E. coli),Iron sulfur cluster scaffold homolog,Iron-sulfur cluster assembly enzyme ISCU,Iscu,IscU iron sulfur cluster scaffold homolog,ISCU,ISU2,MGC74517,mitochondrial,NIFU,NifU like N terminal domain containing,NifU like N terminal domain containing protein,NifU like protein,NifU-like N-terminal domain-containing protein,NifU-like protein,NIFUN,Nitrogen fixation cluster like,OTTHUMP00000238760,OTTHUMP00000238761,OTTHUMP00000238762,OTTHUMP00000238764,OTTHUMP00000238765,ISCU抗体 |
| Swissprot | Q9H1K1 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ISCU |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.96mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus and Mitochondrion. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1. |
