ITGAE Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15139
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | A530055J10,alpha-E1,alpha-M290,aM290,Antigen CD103,CD 103,CD103,CD103 antigen,HML 1 antigen,HML-1 antigen,HML1 antigen,Human mucosal lymphocyte antigen 1,Human mucosal lymphocyte antigen 1,alpha subunit,Huminae,Integrin alpha E heavy chain,Integrin alpha E light chain,Integrin alpha E,epithelial-associated,Integrin alpha E1,Integrin alpha IEL,Integrin alpha M290,Integrin alpha-E heavy chain,Integrin alpha-IEL,Integrin,alpha E (antigen CD103,human mucosal lymphocyte antigen 1,alpha polypeptide),Integrin,alpha E,ITAE,Itgae,MGC141996,MGC183601,Mucosal lymphocyte 1 antigen,Mucosal lymphocyte antigen 1,ITGAE抗体 |
| Swissprot | P38570 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human ITGAE |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. |
