ITGAV Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70153
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | antigen identified by monoclonal L230,CD 51,CD51,DKFZp686A08142,Integrin alpha five,integrin alpha V beta 3,Integrin alpha-5,integrin alpha-V,Integrin alpha-V light chain,integrin alphaVbeta3,integrin,alpha V (vitronectin receptor,alpha polypeptide,antigen CD51),ITAV,ITGAV,MSK 8,Msk8,Vitronectin receptor subunit alpha,VNRA,VTNR,ITGAV抗体 |
| Swissprot | P06756,P43406 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:300-1:1000 |
| Concentration | 470 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell junction, Cell membrane, Membrane |
| Tissue specificity | Highest expression level in pigmented layer of retina |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
Images
Immunohistochemistry analysis of paraffin-embedded human liver cancer using ITGAV Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse kidney using ITGAV Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded Rat brain using ITGAV Polyclonal Antibody at dilution of 1:400.
