ITGB1BP1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-53077
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | Bodenin,DKFZp686K08158,ICAP 1,ICAP 1A,ICAP 1alpha,ICAP 1B,ICAP-1,ICAP-1A,ICAP-1alpha,ICAP-1B,ICAP1,ICAP1A,ICAP1B,Integrin beta 1 binding protein 1,Integrin beta-1-binding protein 1,Integrin cytoplasmic domain associated protein 1 alpha,Integrin cytoplasmic domain associated protein 1,Integrin cytoplasmic domain associated protein 1 beta,Integrin cytoplasmic domain-associated protein 1,ITBP1,ITGB1BP1,ITGB1BP1抗体 |
Swissprot | O14713 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Fusion protein of human ITGB1BP1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:100 |
Concentration | 1.02mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. |