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ITGB1BP1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-53077

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms Bodenin,DKFZp686K08158,ICAP 1,ICAP 1A,ICAP 1alpha,ICAP 1B,ICAP-1,ICAP-1A,ICAP-1alpha,ICAP-1B,ICAP1,ICAP1A,ICAP1B,Integrin beta 1 binding protein 1,Integrin beta-1-binding protein 1,Integrin cytoplasmic domain associated protein 1 alpha,Integrin cytoplasmic domain associated protein 1,Integrin cytoplasmic domain associated protein 1 beta,Integrin cytoplasmic domain-associated protein 1,ITBP1,ITGB1BP1,ITGB1BP1抗体
    Swissprot O14713
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human ITGB1BP1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:100
    Concentration 1.02mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.
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