KCNIP1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52076
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | A type potassium channel modulatory protein 1,A-type potassium channel modulatory protein 1,KChIP1,KCIP1,Kcnip1,Kv channel interacting protein 1,Kv channel-interacting protein 1,MGC9,MGC95,Potassium channel interacting protein 1,Potassium channel-interacting protein 1,VABP,Vesicle APC binding protein,Vesicle APC-binding protein,KCNIP1抗体 |
Swissprot | Q9NZI2 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human KCNIP1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 1.2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. Cytoplasm. Cell projection, dendrite. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains,and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents,and hence neuronal excitability,in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels,GABAergic transmission and cell death. |