KCNJ10 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53181
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | inwardly rectifying subfamily J member 10,ATP dependent inwardly rectifying potassium channel Kir4.1,ATP sensitive inward rectifier potassium channel 10,ATP-dependent inwardly rectifying potassium channel Kir4.1,ATP-sensitive inward rectifier potassium channel 10,BIRK10,Glial ATP dependent inwardly rectifying potassium channel KIR4.1,Inward rectifier K(+) channel Kir1.2,Inward rectifier K+ channel KIR1.2,Inwardly rectifying potassium channel Kir1.2,KCJ10,KCNJ 10,Kcnj10,KCNJ13 PEN,KIR1.2,KIR4.1,Potassium channel,Potassium channel inwardly rectifying subfamily J member 10,Potassium inwardly rectifying channel subfamily J member 10,SESAME,KCNJ10抗体 |
| Swissprot | P78508 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human KCNJ10 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:100 |
| Concentration | 1.02mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. Basolateral cell membrane. In kidney distal convoluted tubules, located in the basolateral membrane where it colocalizes with KCNJ16. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | KCNJ10 (Potassium Voltage-Gated Channel Subfamily J Member 10) is a Protein Coding gene. Diseases associated with KCNJ10 include Sesame Syndrome and Deafness, Autosomal Recessive 4, With Enlarged Vestibular Aqueduct. Among its related pathways are Inwardly rectifying K+ channels and GABA receptor activation. GO annotations related to this gene include identical protein binding and potassium channel activity. An important paralog of this gene is KCNJ15.This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. |
