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KLF7 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10417

宿主: Rabbit

反应性: H,M

应用: WB,IHC,ELISA

  • 详情
  • 文献(1)
  • Overview

    Synonyms KLF7,KLF7,Krueppel like factor 7,Krueppel-like factor 7,Kruppel like factor 7,Ubiquitous krueppel like factor,Ubiquitous krueppel-like factor,UKLF,KLF7抗体
    Swissprot O75840
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Recombinant protein of human KLF7
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
    Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
    Concentration 0.7 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Tissue specificity Ubiquitous and highly expressed in brain and spinal cord in the adult, and in kidney and brain in the embryo.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
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