KLK10 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40295
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | Breast normal epithelial cell associated serine protease,Kallikrein related peptidase 10,Kallikrein10,KLK 10,KLK10,NES 1,NES1,Normal epithelial cell-specific 1,Protease serine like 1,Protease serine-like 1,PRSS L1,PRSSL 1,PRSSL1,KLK10抗体 |
| Swissprot | P36375 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant Rat Glandular kallikrein-10 protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.97mg/mL |
Properties
| Cellular localization | Secretory granule |
| Tissue specificity | Kidney and submandibular gland, where it is found in the granular convoluted tubule and striated duct cells. It is likely that the enzyme is mainly synthesized in the granular convoluted tubules and then transferred to other tissues by release into the vasculature or interstitial space.Highest expression level in adult mammalian kidney. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. |
Images
Immunohistochemistry of paraffin-embedded Rat kidney using KLK10 Polyclonal Antibody Antibody at dilution of 1:200(1×100)
Immunohistochemistry of paraffin-embedded Rat kidney using KLK10 Polyclonal Antibody Antibody at dilution of 1:200(1×400)
Immunohistochemistry of paraffin-embedded Mouse kidney using KLK10 Polyclonal Antibody Antibody at dilution of 1:200
