KLK10 Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：D-AB-10185L
货期：咨询
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | Breast normal epithelial cell associated serine protease,Kallikrein related peptidase 10,Kallikrein10,KLK 10,KLK10,NES 1,NES1,Normal epithelial cell-specific 1,Protease serine like 1,Protease serine-like 1,PRSS L1,PRSSL 1,PRSSL1 |
| Swissprot | O43240 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human KLK10 protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:1000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Tissue specificity | Expressed in breast, ovary and prostate.Highest expression level in lower esophagus mucosa. |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. |
