KLK6 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40296
宿主: Rabbit
反应性: H,M,R
应用: IHC,IF
Overview
Synonyms | Kallikrein related peptidase 6, Klk-8, Klk8, Kallikrein-6, KLK 6, MGC9355, mGK 1, mGK1, MSP, PRSS 18, PRSS 9,KLK6抗体 |
Swissprot | P36374 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant Rat Prostatic glandular kallikrein-6 protein |
Application | IHC(Detection kit: E-IR-R213),IF |
Recommended dilution | IHC 1:100-1:300 IF 1:100-1:200 |
Concentration | 0.3mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted, Nucleus > nucleolus, Cytoplasm |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. |
Images
Immunohistochemistry of paraffin-embedded Human colorectal cancer using KLK6 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human breast using KLK6 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Rat kidney using KLK6 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Mouse kidney using KLK6 Polyclonal Antibody at dilution of 1:200
Immunofluorescence analysis of U-2OS cells using KLK6 Polyclonal Antibody at dilution of 1:100