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KLK6 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-40296

宿主: Rabbit

反应性: H,M,R

应用: IHC,IF

  • 详情
  • Overview

    Synonyms Kallikrein related peptidase 6, Klk-8, Klk8, Kallikrein-6, KLK 6, MGC9355, mGK 1, mGK1, MSP, PRSS 18, PRSS 9,KLK6抗体
    Swissprot P36374
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant Rat Prostatic glandular kallikrein-6 protein
    Application IHC(Detection kit: E-IR-R213),IF
    Recommended dilution IHC 1:100-1:300 IF 1:100-1:200
    Concentration 0.3mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted, Nucleus > nucleolus, Cytoplasm
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
    Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
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