Laminin alpha5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-31903
宿主: Rabbit
反应性: H,M
应用: WB,IHC-p
Overview
| Synonyms | LAMA5,KIAA0533,KIAA1907,Laminin subunit alpha-5,Laminin-10 subunit alpha,Laminin-11 subunit alpha,Laminin-15 subunit alpha,Laminin α-5抗体 |
| Swissprot | O15230 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from the Internal region of human Laminin α-5 |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Extracellular region or secreted,basal lamina,basement membrane,extracellular exosome,extracellular matrix,extracellular region,extracellular space,laminin-10 complex,laminin-11 complex,laminin-5 complex,synaptic cleft,Nucleus |
| Tissue specificity | Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. |
客户发表文献
- 文献: Three kinds of corneal host cells contribute differently to corneal neovascularization
样品类型: Tissue homogenate - 文献: Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract
样品类型: anterior lens capsules (ALCs),HLE B-3 cells - 文献: Kojic acid inhibits senescence of human corneal endothelial cells via NF-κB and p21 signaling pathways
样品类型: Cell lysate
