Leptin R Polyclonal Antibody(Capture/Detector)
规格: | / 25μg / 100μg |
价格: | / ¥800 / ¥2100 |
货号:AN000990P
货期:咨询
宿主: Rabbit
反应性: M
应用: ELISA Capture/Detector
Overview
Synonyms | CD295;LEP-R;LR;LEPRD;OB-R;OBR; |
Swissprot | P48356 |
Source | Rabbit |
Reactivity | Mouse |
Immunogen | Recombinant Mouse Leptin R protein expressed by Mammalian |
Application | ELISA Capture/Detector |
Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Storage buffer | Sterile PBS,pH 7.4 |
Background | The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021). |