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LILRB5 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19513

宿主: Rabbit

反应性: H

应用: WB,IHC

  • 详情
  • Overview

    Synonyms CD85 antigen-like family member C,CD85c,Leukocyte immunoglobulin-like receptor 8,Leukocyte immunoglobulin-like receptor subfamily B member 5,LILRB5,LIR-8,LIR8,LIRB5,LILRB5抗体
    Swissprot O75023
    Source Rabbit
    Reactivity Human
    Immunogen Synthetic peptide of human LILRB5
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:10-1:50;
    Concentration 0.72mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.
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