LILRB5 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19513
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | CD85 antigen-like family member C,CD85c,Leukocyte immunoglobulin-like receptor 8,Leukocyte immunoglobulin-like receptor subfamily B member 5,LILRB5,LIR-8,LIR8,LIRB5,LILRB5抗体 |
Swissprot | O75023 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human LILRB5 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:10-1:50; |
Concentration | 0.72mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. |