MAP2K6 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40167
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | MEK6,MKK6,MAPKK6,PRKMK6,SAPKK3,SAPKK-3,MAP2K6抗体 |
| Swissprot | P70236 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant Mouse Dual specificity mitogen-activated protein kinase kinase 6 protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:100 |
| Concentration | 2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoskeleton,Cytosol,Nucleus,nucleoplasm,nucleus,Other locations:cytoplasm |
| Tissue specificity | Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. |
