MARK2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17851
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | ELKL motif kinase 1,ELKL motif kinase,EMK-1,EMK1,MAP/microtubule affinity regulating kinase 2,MAP/microtubule affinity-regulating kinase 2,Mark2,MARK2,MGC99619,PAR 1,Par 1b,PAR1 homolog,Par1b,Ser/Thr protein kinase PAR 1B,Serine/threonine protein kinase EMK,Serine/threonine protein kinase MARK2,Serine/threonine-protein kinase MARK2,MARK2抗体 |
Swissprot | Q7KZI7 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human MARK2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
Concentration | 0.9mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. Phosphorylated by PRKCZ in polarized epithelial cells, resulting in an interaction with YWHAZ which promotes relocation from the lateral to the apical membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. |