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MARK2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17851

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms ELKL motif kinase 1,ELKL motif kinase,EMK-1,EMK1,MAP/microtubule affinity regulating kinase 2,MAP/microtubule affinity-regulating kinase 2,Mark2,MARK2,MGC99619,PAR 1,Par 1b,PAR1 homolog,Par1b,Ser/Thr protein kinase PAR 1B,Serine/threonine protein kinase EMK,Serine/threonine protein kinase MARK2,Serine/threonine-protein kinase MARK2,MARK2抗体
    Swissprot Q7KZI7
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human MARK2
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:25-1:100;
    Concentration 0.9mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane. Phosphorylated by PRKCZ in polarized epithelial cells, resulting in an interaction with YWHAZ which promotes relocation from the lateral to the apical membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
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