MC2R Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-12555
宿主: Rabbit
反应性: H,M
应用: WB
Overview
Synonyms | ACTH receptor,ACTH-R,ACTHR,ACTHR,Adrenocorticotropic hormone receptor,Adrenocorticotropin receptor,Corticotropin receptor,MC2 receptor,MC2-R,MC2R,Melanocortin 2 receptor (adrenocorticotropic hormone),Melanocortin 2 receptor,Melanocortin receptor 2,MC2R抗体 |
Swissprot | Q01718 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Synthetic peptide of human MC2R |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:1000-1:5000; |
Concentration | 0.5 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. |
Tissue specificity | Melanocytes and corticoadrenal tissue. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. |