MCL1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16255
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Bcl 2 related protein EAT/mcl1,Bcl-2-like protein 3,Bcl-2-related protein EAT/mcl1,BCL2 related,Bcl2-L-3,BCL2L3,EAT,Induced myeloid leukemia cell differentiation protein Mcl 1,Induced myeloid leukemia cell differentiation protein Mcl-1,MCL 1,MCL1,MCL1-ES,mcl1/EAT,MCL1,MCL1L,MCL1S,MGC104264,MGC1839,Myeloid Cell Leukemia 1,Myeloid cell leukemia ES,Myeloid cell leukemia sequence 1,Myeloid cell leukemia sequence 1 BCL2 related,Myeloid cell leukemia sequence 1 isoform 1,OTTHUMP00000032794,OTTHUMP00000032795,TM,MCL1抗体 |
| Swissprot | Q07820 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human MCL1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. Cytoplasm. Mitochondrion. Nucleus>nucleoplasm. Cytoplasmic, associated with mitochondria. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. |
