MEF2D Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53508
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | DKFZp686I1536,MADS box transcription factor 2 polypeptide D,Mef2d,MEF2D,Myocyte enhancer factor 2D,Myocyte specific enhancer factor 2,polypeptide D,Myocyte specific enhancer factor 2D,Myocyte-specific enhancer factor 2D,MEF2D抗体 |
| Swissprot | Q14814 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human MEF2D |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:35-1:200 |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Translocated by HDAC4 to nuclear dots. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. MEF2D (Myocyte Enhancer Factor 2D) is a Protein Coding gene. Among its related pathways are Phospholipase-C Pathway and Development Angiotensin activation of ERK. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is MEF2A. |
