MFN2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-32025
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC-p
Overview
| Synonyms | CMT2A,CMT2A2,CPRP 1,CPRP1,EC 3.6.5.-,Fzo,HSG,hyperplasia suppressor gene,Hypertension related protein 1,KIAA0214,MARF,MFN 2,Mfn2,MFN2,Mitochondrial assembly regulatory factor,Mitofusin-2,Mitofusin2,Transmembrane GTPase MFN2,Mfn2抗体 |
| Swissprot | O95140 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from the Internal region of human Mfn2. |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion outer membrane. Colocalizes with BAX during apoptosis. |
| Tissue specificity | Ubiquitous; expressed at low level. Highly expressed in heart and kidney. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. |
