MITF Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3580 |
货号:E-AB-60287
宿主: Rabbit
反应性: H,M
应用: WB
Overview
Synonyms | MITF,CMM8,COMMAD,MI,WS2,WS2A,bHLHe32,MITF抗体 |
Swissprot | O75030 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Recombinant fusion protein of human MITF (NP_937801.1). |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,, 1:500-1:2000; |
Concentration | 1 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Background | This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. |