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MITF Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3580

货号:E-AB-60287

宿主: Rabbit

反应性: H,M

应用: WB

  • 详情
  • 文献(1)
  • Overview

    Synonyms MITF,CMM8,COMMAD,MI,WS2,WS2A,bHLHe32,MITF抗体
    Swissprot O75030
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Recombinant fusion protein of human MITF (NP_937801.1).
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,, 1:500-1:2000;
    Concentration 1 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20°C. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3
    Background This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
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