MMP17 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12569
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | Matrix metalloproteinase 17,Matrix metalloproteinase 17 membrane inserted,Matrix metalloproteinase-17,Membrane type 4 matrix metalloproteinase,Membrane type matrix metalloproteinase 4,Membrane-type matrix metalloproteinase 4,Membrane-type-4 matrix metalloproteinase,MMP 17,MMP-17,Mmp17,MMP17,MT MMP 4,MT MMP4,MT-MMP 4,MT4 MMP,MT4-MMP,MT4MMP,MTMMP 4,MTMMP4,MMP17抗体 |
| Swissprot | Q9ULZ9 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human MMP17 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Secreted>extracellular space>extracellular matrix. |
| Tissue specificity | Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily.However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein.The protein activates MMP-2 by cleavage. |
