MT-ND1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13427
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Complex I,subunit ND1,Mitochondrially encoded NADH dehydrogenase 1,MT-ND1,MTND1,NAD1,NADH dehydrogenase subunit 1 (complex I),NADH dehydrogenase subunit 1,NADH-ubiquinone oxidoreductase chain 1,NADH-ubiquinone oxidoreductase,subunit ND1,NADH1,ND1,NU1M,MT-ND1抗体 |
| Swissprot | P03886 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human MT-ND1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:200-1:1000;IHC,,1:50-1:200; |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion inner membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease. |
Images
Western Blot analysis of Hela cell using MT-ND1 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human thyroid cancer using MT-ND1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human brain using MT-ND1 Polyclonal Antibody at dilution of 1:50
