MUC5B Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15988
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | 2300002I04Rik,A130042M24,AV085033,Cervical mucin,Cervical mucin MUC5B,High molecular weight salivary mucin MG1,MG1,MUC-5B,MUC5,MUC5B,MUC5B,MUC9,Mucin 5 subtype B,tracheobronchial,Mucin 5B,Mucin 5B oligomeric mucus/gel forming,Mucin-5 subtype B,Mucin-5B,Sublingual gland mucin,tracheobronchial,MUC5B抗体 |
| Swissprot | Q9HC84 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human MUC5B |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Tissue specificity | Expressed on surface airway epithelia. Expressed mainly in mucous cells of submucosal glands of airway tissues. Highly expressed in the sublingual gland. Also found in submaxillary glands, endocervix, gall bladder, and pancreas. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. |
客户发表文献
- 文献: Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD
样品类型: Tissue homogenate - 文献: Mucus Hypersecretion and Ciliary Impairment in Conducting Airway Contribute to Alveolar Mucus Plugging in Idiopathic Pulmonary Fibrosis.
样品类型: bronchial submucosal region,airway,lung - 文献: Chr15q25 Genetic Variant rs16969968 Alters Cell Differentiation in Respiratory Epithelia
样品类型: lung - 文献: Effective-compound combination of Bufei Yishen formula III combined with ER suppress airway mucus hypersecretion in COPD rats: via EGFR/MAPK signaling
样品类型: lung tissues
