MYD88 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70128
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | Mutant myeloid differentiation primary response 88,MYD 88,Myd88,MYD88,MYD88D,Myeloid differentiation marker 88,Myeloid differentiation primary response 88,Myeloid differentiation primary response gene (88),Myeloid differentiation primary response gene 88,Myeloid differentiation primary response gene,Myeloid differentiation primary response protein MyD88,OTTHUMP00000161718,OTTHUMP00000208595,OTTHUMP00000209058,OTTHUMP00000209059,OTTHUMP00000209060,MYD88抗体 |
| Swissprot | P22366,Q6Y1S1 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse MYD88 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:400 |
| Concentration | 110 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Tissue specificity | Detected in bone marrow. Isoform 1 is expressed in testis, kidney, lung, ovary, adrenal gland, provstate, thymus and heart, and weakly in skeletal muscle, liver, spleen and brain. Isoform 2 is mainly expressed in the spleen and weakly in brain.Highest expression level in blood. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. |
