NAE1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14592
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
| Synonyms | 59 kDa,A 116A10.1,Amyloid beta precursor protein binding protein 1 59kD,Amyloid beta precursor protein binding protein 1 59kDa,Amyloid beta precursor protein binding protein 1,Amyloid beta precursor protein binding protein 1,59 kDa,Amyloid beta precursor protein-binding protein 1,Amyloid protein binding protein 1,Amyloid protein-binding protein 1,APP BP1,APP-BP1,APPBP 1,APPBP1,HPP 1,HPP1,NAE 1,NAE1,NEDD8 activating enzyme E1 regulatory subunit,NEDD8 activating enzyme E1 subunit 1,NEDD8 activating enzyme E1 subunit,NEDD8-activating enzyme E1 regulatory subunit,Proto oncogene protein 1,Proto-oncogene protein 1,Protooncogene protein 1,ula 1,ULA1,NAE1抗体 |
| Swissprot | Q13564 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human NAE1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:200-1:1000; |
| Concentration | 0.1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Colocalizes with APP in lipid rafts. |
| Tissue specificity | Ubiquitous in fetal tissues. Expressed throughout the adult brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
