NDUFS2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-16636
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | CI 49,CI 49kD,CI-49kD,Complex 1,mitochondrial respiratory chain,49 KD subunit,Complex I 49kD,Complex I 49kDa subunit,Complex I-49kD,mitochondrial,NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa,NADH dehydrogenase (ubiquinone) Fe S protein 2,49kDa (NADH coenzyme Q reductase),NADH dehydrogenase [ubiquinone] iron sulfur protein 2,mitochondrial,NADH dehydrogenase [ubiquinone] iron-sulfur protein 2,NADH ubiquinone oxidoreductase 49 kDa subunit,NADH ubiquinone oxidoreductase NDUFS2 subunit,NADH-ubiquinone oxidoreductase 49 kDa subunit,NADH:ubiquinone oxidoreductase core subunit S2,Ndufs2,NDUS2,NDUFS2抗体 |
Swissprot | O75306 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human NDUFS2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
Concentration | 0.7mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion inner membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Images
Western Blot analysis of Mouse heart and brain tissue, Jurkat cell using NDUFS2 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human ovarian cancer using NDUFS2 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using NDUFS2 Polyclonal Antibody at dilution of 1:50