NFATC4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40328
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | cytoplasmic 4,NF ATc4,NF-AT3,NF-ATc4,NFAC4,NFAT3,NFATc4,Nuclear factor of activated T cells cytoplasmic 4,Nuclear factor of activated T cells cytoplasmic calcineurin dependent 4,Nuclear factor of activated T-cells,T cell transcription factor NFAT3,T-cell transcription factor NFAT3,NFATC4抗体 |
| Swissprot | Q14934 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human Nuclear factor of activated T-cells protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC 1:100-1:400 |
| Concentration | 2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. |
| Tissue specificity | Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Background | The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
