NOS3 Polyclonal Antibody
| 规格： | / 20 μL / 60 μL / 120 μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-32267
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC-p,IF
Overview
| Synonyms | cNOS,Constitutive NOS,EC NOS,EC-NOS,ecNOS,Endothelial nitric oxidase synthase,Endothelial nitric oxide synthase,Endothelial nitric oxide synthase 3,Endothelial NOS,eNOS,Nitric oxide synthase 3 (endothelial cell),Nitric oxide synthase 3,Nitric oxide synthase 3 endothelial cell,Nitric oxide synthase endothelial,Nitric oxide synthase,endothelial,NOS 3,NOS III,NOS type III,NOS3,NOS3,NOSIII |
| Swissprot | P29474 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from human NOS3 around the non-phosphorylation site of Ser1177. |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:200-1:1000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle and which is favored by interaction with NOSIP and results in a reduced enzymatic activity. |
| Tissue specificity | Platelets, placenta, liver and kidney. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. |
客户发表文献
- 文献: Thymoquinone regulates nitric oxide synthase enzymes and receptor-interacting serine-threonine kinases in isoproterenol-induced myocardial infarcted rats
样品类型: heart tissue - 文献: Changes in Histological Structure, Interleukin 12, Smooth Muscle Actin and Nitric Oxide Synthase 1. and 3. Expression in the Liver of Running and Non-Running Wistar Rats Supplemented with Bee Pollen or Whey Protein
样品类型: liver
