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NRAS Polyclonal Antibody

规格: / 50μL / 100μL
价格: / ¥1010 / ¥1640

货号:D-AB-10191L

货期:咨询

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms ALPS4,AV095280,GTPase NRas,HRAS1,N ras,N ras protein part 4,Neuroblastoma RAS viral (v ras) oncogene homolog,NRAS,NRAS1,NS6,OTTHUMP00000013879,OTTMUSP00000023521,RASN,Transforming protein N Ras,Transforming protein N-Ras,v ras neuroblastoma RAS viral oncogene homolog
    Swissprot P01111
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant Human NRAS protein expressed by E.coli
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:1000;IF,,1:50-1:200;
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell Membrane, Cytoplasmic and Golgi Apparatus.
    Tissue specificity Highest expression level in testi
    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
    Background This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. 
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