NRAS Polyclonal Antibody
规格: | / 50μL / 100μL |
价格: | / ¥1010 / ¥1640 |
货号:D-AB-10191L
货期:咨询
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | ALPS4,AV095280,GTPase NRas,HRAS1,N ras,N ras protein part 4,Neuroblastoma RAS viral (v ras) oncogene homolog,NRAS,NRAS1,NS6,OTTHUMP00000013879,OTTMUSP00000023521,RASN,Transforming protein N Ras,Transforming protein N-Ras,v ras neuroblastoma RAS viral oncogene homolog |
Swissprot | P01111 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant Human NRAS protein expressed by E.coli |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:1000;IF,,1:50-1:200; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell Membrane, Cytoplasmic and Golgi Apparatus. |
Tissue specificity | Highest expression level in testi |
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
Background | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. |