NSMCE3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16215
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | HCA4,hepatocellular carcinoma-associated protein 4,hepatocellular carcinoma-associated protein HCA4,MAGE-G1 antigen,MAGEG1,MAGEL3,melanoma antigen,family G,1,melanoma-associated antigen G1,necdin-like 2,necdin-like gene 2,necdin-like protein 2,NSE3,NSMCE3,NDNL2抗体 |
| Swissprot | Q96MG7 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human NDNL2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 1.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasmic and Nuclear |
| Tissue specificity | Ubiquitous.1 Publication |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). |
Images
Western Blot analysis of Hela cell and Human prostate tissue, A172 cell and Mouse liver tissue using NSMCE3 Polyclonal Antibody at dilution of 1:1500
Immunohistochemistry of paraffin-embedded Human breast cancer using NSMCE3 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human esophagus cancer using NSMCE3 Polyclonal Antibody at dilution of 1:40
